Improvements in the welfare of humans and health largely depend on research that uses human participants. In order to validate results concerning causes of diseases, human physiology, efficiency of treatment, or behaviour, adequately controlled research that uses participation of human participants is required (Spellecy & Busse., 2021) Unfortunately, some human research has not been justified and beneficial. In the guise of scientific advancement, human brutality can and has been committed. In Nazi Germany, well-known incidents happened. Following the war, investigations found that atrocities had been committed in the name of research. An example are tests in which subjects were put in water that was very cold to assess the time it would take to succumb from hypothermia (n. d ., 2017) The trials of Nuremberg and the Nuremberg Code (1949), which was the premier global code of basic standards for the research conduct when dealing with humans, were based on the discovery of these abominations (n. d ., 2017) An important aspect of the code was that experiments should be justified and the participants should be willing (PMC, 2020)
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